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Medchemexpress LLC Mira-1 | 72835-26-8 | 99.8% | 183.16 g/mol | C8H9NO4 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1086395MG

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MIRA-1 (NSC 19630) is a maleimide-derived small-molecule research compound that restores wild-type conformation and transcriptional activity to mutant p53, triggering p53-dependent transcriptional transactivation and apoptosis in mutant p53 cancer cells. It has reported anticancer activity and an IC50 of approximately 10 μM against Saos-2 His273 cells. Provided as a high-purity reagent for in vitro and in vivo studies.

  • Molecular formula: C8H9NO4.
  • Molecular weight: 183.16 g/mol.
  • Purity: 99.76%.
  • Solubility: DMSO 100 mg/mL; in vivo vehicles soluble ≥2.5 mg/mL.
  • Suggested storage: powder -20°C for long term; in solvent -80°C recommended.
  • Reported activity: induces p53-dependent transcriptional transactivation and apoptosis.

Catalog No. 50-002-64267


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