Apexbio Technology LLC Mirabegron (YM178) 223673-61-8 10mM (in 1mL DMSO)

Supplier:  Apexbio Technology LLC A84745.1

Mirabegron (YM178 CAS 223673-61-8) is a selective agonist targeting the -adrenergic receptor ( -AR) Activation of -AR influences physiological responses in tissues including adipose cells prostate gastrointestinal tract and primarily the urinary bladder In CHO cells expressing human -adrenergic receptor subtypes mirabegron demonstrated selective agonist properties at -AR (EC 22 4 nM) showing minimal activity at - and -AR subtypes Animal studies revealed mirabegron reduced rhythmic bladder contraction frequency without affecting amplitude Its selective -AR agonist profile makes mirabegron pertinent for research on bladder dysfunction particularly overactive bladder conditions

Catalog No. 50-000-61842