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Medchemexpress LLC Miransertib hydrochloride | 1313883-00-9 | 99.7% | 468.98 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY19719A50MG

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Miransertib hydrochloride is a potent, orally active, selective, and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM, and 8.1 nM for Akt1, Akt2, and Akt3. It is a potent AKT1-E17K mutant protein inhibitor and has potential for research on PI3K/AKT-driven tumors and Proteus syndrome. It is also effective against Leishmania.

  • Potent, orally active, selective, and allosteric Akt inhibitor
  • Inhibitor of the AKT1-E17K mutant protein
  • Potential for research into PI3K/AKT-driven tumors and Proteus syndrome
  • Effective against Leishmania
  • Good absolute oral bioavailability in rats and monkeys
  • Inhibits tumor growth in a human xenograft mouse model of endometrial adenocarcinoma

Catalog No. 50-004-02775


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