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Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 1 ML
Supplier: Medchemexpress LLC HYB035210MM/1ML
Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It functions as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist. Mirtazapine enhances the release of norepinephrine and 5-HT1A-mediated serotonergic transmission.
- Antagonizes adrenergic α2-autoreceptors and α2-heteroreceptors
- Blocks 5-HT2 and 5-HT3 receptors
- Enhances norepinephrine release
- Enhances 5-HT1A-mediated serotonergic transmission
- Reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes
- Inhibits hepatic macrophage/monocyte activation and decreases pro-inflammatory cytokine and chemokine production
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