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Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 200 MG

Supplier: Medchemexpress LLC HYB0352200MG
Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist. Its metabolism is primarily handled by cytochrome P450 isoenzymes CYP1A2, CYP2D6, and CYP3A4.
- Acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist
- Enhances norepinephrine and 5-HT1A-mediated serotonergic transmission
- Significantly reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes
- Inhibits Con A-induced liver injury by suppressing hepatic macrophage/monocyte activation
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