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Medchemexpress LLC Mito-TEMPO | 1334850-99-5 | 99.19% | 510.03 | 25 MG
Supplier: Medchemexpress LLC 25MGHY112879
Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic with superoxide and alkyl radical scavenging properties.
- Mito-TEMPO greatly attenuates the increase in ALT activities and reduces the areas of necrosis at both time points, indicating that the protection is sustained until at least 24 h post-APAP.
- Mito-TEMPO could induce secondary apoptosis in the late phase of APAP hepatotoxicity.
- Mito-TEMPO induces secondary apoptosis after APAP overdose by inhibition of RIP3.
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