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Medchemexpress LLC Mito-TEMPO | 1334850-99-5 | 99.2% | 510.03 | 1 ML
Supplier: Medchemexpress LLC HY11287910MM/1ML
Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic with superoxide and alkyl radical scavenging properties. It significantly reduces the increase in ALT activities and areas of necrosis, indicating sustained protection during acetaminophen-induced hepatotoxicity. Mito-TEMPO can also induce secondary apoptosis in the late phase of APAP hepatotoxicity by inhibiting RIP3.
- Mitochondria-targeted
- Superoxide dismutase mimetic
- Superoxide and alkyl radical scavenging properties
- Attenuates increases in ALT activities and reduces necrosis areas in acute liver injury
- Induces secondary apoptosis in APAP hepatotoxicity via RIP3 inhibition
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