Cayman Chemical MItoBloCK-10 50mg

Supplier:  Cayman Chemical 4205450 MG

A mitochondrial protein import inhibitor; inhibits the import of cytochrome c1 into the mitochondrial intermembrane space in yeast cells at 100 µM; inhibits migration and invasion of, and induces apoptosis and cell cycle arrest at the G1 phase in, primary human bladder cancer cells at 25 µM; induces mitochondrial depolarization, decreases ATP levels, and increases ROS in primary human bladder cancer cells; decreases tumor volume in a PDX mouse model of bladder cancer at 20 mg/kg every other day; intravitreal administration reduces SOD activity and increases TBARS levels and acellular capillary numbers in mouse retina at 0.25 nM/eye; induces dorsal curvature and cardiac apoptosis in zebrafish embryos at 10 µM

Catalog No. 50-297-8463