Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Sigma Aldrich Fine Chemicals Biosciences Mitomycin C ready made sol
Supplier: Sigma Aldrich Fine Chemicals Biosciences M53535X0.2ML
Mitomycin C (MMC) produced by Streptomyces caespitosus is an anticancer antibiotic agent which inhibits proliferation of various cell types in vitro. MMC is DNA alkylating agent that causes cross linking of complementary DNA strands resulting in mutagenesis inhibition of DNA synthesis initiation of DNA repair events and activation of apoptosis. furthermore MMC has an effect on ribosomal RNA leading to protein synthesis inhibition.MMC is capable of inhibiting cell proliferation of human or murine embryonic fibroblast cells at concentration range of 0.2-20mug/mL. These treated cells are subsequently used as an adherent feeder layer in long-term culture assays mainly for growth of pluripotent stem cells. feeder layer cells support the target cells by releasing growth factors to the cell culture and detoxification of the medium. Moreover feeder layer cells play a role in ECM proteins synthesis that controls cell culture growth. In addition feeder layer cells are used as a substrate
Description
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction