Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Mizagliflozin | 666843-10-3 | 99.2% | 564.67 | 50 MG
Supplier: Medchemexpress LLC HY1763850MG
Mizagliflozin (DSP-3235 free base) is a potent, orally active, and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. It displays 303-fold selectivity over SGLT2. This compound functions as an antidiabetic agent capable of modifying postprandial blood glucose excursion and also shows potential in the amelioration of chronic constipation. In vivo, the compound at doses of 3-30 mg/kg orally has a laxative effect, increasing fecal wet weight in a rat model of low-fiber-diet-induced constipation. The compound has a short half-life, with 0.23 h after intravenous administration and 1.14 h after oral administration.
- Highly selective SGLT1 inhibitor
- Helps manage postprandial blood glucose levels
- Potential to treat chronic constipation
- Orally active for convenient administration
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?