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Medchemexpress LLC Mk-0812 succinate | 851916-42-2 | 99.94% | C28H40F3N3O7 | 100 MG
Supplier: Medchemexpress LLC HY50669A100MG
MK-0812 Succinate is a potent and selective CCR2 antagonist with high affinity. It completely blocks all MCP-1 mediated responses in a concentration-dependent manner. It also inhibits 125I-MCP-1 binding on isolated monocytes. The compound blocks the shape change response to exogenous MCP-1 and reduces the frequency of Ly6G-Ly6Chi monocytes in peripheral blood in vivo.
- Potent and selective CCR2 antagonist
- High affinity at CCR2
- Blocks all MCP-1 mediated responses
- Inhibits 125I-MCP-1 binding on isolated monocytes
- Reduces Ly6G-Ly6Chi monocytes in peripheral blood in vivo
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