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Apexbio Technology LLC MK-4827, 10mg. Cas: 1038915-60-4 MFCD: MFCD17779309. PARP-1/-2 inhibitor,potent and selective

Supplier: Apexbio Technology LLC A361710

MK-4827 is a novel, selective and orally bioavailable PARP1/PARP2 inhibitor with IC50 of 3.8 nM and 2.1 nM, respevctively.MK-4827 has shown great activity against cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1 [1]. Other sizes are available. Please inqury us for quote.
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