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Apexbio Technology LLC MK-4827-TOSYLATE-2MG
SDP

Catalog No. 5000567997
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MK-4827 tosylate (CAS No 1038915-73-9) is a small molecule inhibitor primarily researched in the oncology field originating from studies on targeting DNA repair pathways It specifically inhibits poly (ADP-ribose) polymerase (PARP) enzymes which are crucial in the repair of single-strand DNA breaks thus leading to the accumulation of DNA damage and promoting apoptosis in cancer cells The compound exhibits in vitro activity in the nanomolar range indicating potent efficacy against cancer cell lines with defective BRCA1 or BRCA2 genes Its applications extend to various cell models and animal studies for evaluating anticancer potential and efficacy in drug screening programs Experimental concentrations typically depend on the specific research design ensuring adaptability across different investigative approaches

Catalog No. 50-005-67997 Supplier Apexbio Technology LLC Supplier No. B11642
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MK-4827 tosylate (CAS No 1038915-73-9) is a small molecule inhibitor primarily researched in the oncology field originating from studies on targeting DNA repair pathways It specifically inhibits poly (ADP-ribose) polymerase (PARP) enzymes which are crucial in the repair of single-strand DNA breaks thus leading to the accumulation of DNA damage and promoting apoptosis in cancer cells The compound exhibits in vitro activity in the nanomolar range indicating potent efficacy against cancer cell lines with defective BRCA1 or BRCA2 genes Its applications extend to various cell models and animal studies for evaluating anticancer potential and efficacy in drug screening programs Experimental concentrations typically depend on the specific research design ensuring adaptability across different investigative approaches

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