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Cayman Chemical MK-4827tosylate 10mg
Supplier: Cayman Chemical 2084210 MG
An orally bioavailable inhibitor of PARP1 and PARP2 (IC50s = 3.8 and 2.1 nM, respectively); inhibits the proliferation of BRCA1 and BRCA2 mutant cancer cells in vitro (IC50s = 10-100 nM) and has efficacy alone against a xenograft of BRCA1-deficient cancer in mice
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