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Apexbio Technology LLC MK-5108 (VX-689) 1010085-13-8 10mM (in 1mL DMSO)
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Supplier:  Apexbio Technology LLC A41205.1

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MK-5108 (VX-689 CAS 1010085-13-8) is a selective inhibitor targeting Aurora A kinase (AAK) functioning through competitive interaction with its ATP-binding pocket It exhibits sub-nanomolar inhibition of Aurora A kinase (IC50 0 064 nM) and displays additional inhibitory activity against Aurora B and Aurora C kinases (IC50 14 nM and IC50 12 nM respectively) MK-5108 has been extensively studied in cancer research contexts demonstrating antiproliferative activity across various tumor types including breast cervical colorectal ovarian and pancreatic cancers

Catalog No. 50-000-61541


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