Learn More
Apexbio Technology LLC MK-571 sodium salt hydrate 115103-85-0 50mg

Supplier: Apexbio Technology LLC B803150

MK-571 sodium salt hydrate (CAS 115103-85-0) is an antagonist of the cysteinyl-leukotriene type 1 receptor (CysLT1) a cell-surface receptor mediating allergic and hypersensitivity responses via cysteinyl leukotrienes In addition MK-571 acts as an inhibitor of multidrug resistance-associated protein 2 (ABCC2/Mrp2) commonly employed in vitro to investigate Mrp2-mediated efflux of xenobiotics and conjugates in epithelial cells Experimental evidence with Caco-2/TC7 cells indicates MK-571 also inhibits phase-2 conjugation of flavonols interfering competitively with glucuronide formation Its utilization thus spans immune-related receptor signaling studies and characterizing cellular drug transport mechanisms
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.