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Cayman Chemical MK2a InhIbItr 1mg
Supplier: Cayman Chemical 173251 MG
A substrate-selective p38α MAPK inhibitor; selectively inhibits p38α-dependent phosphorylation of MK2 over ATF2 (Ki = 330 and >20,000 nM, respectively, in cell-free assays); inhibits proliferation of U87, A172, and U251 glioblastoma cells (EC50s = 0.6-1 μM) via inhibition of tubulin polymerization and induction of apoptosis
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