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Apexbio Technology LLC ML 348 899713-86-1 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B49335.1
ML348 (CAS 899713-86-1) is a selective and reversible inhibitor of acyl-protein thioesterase 1 (APT1 also known as LYPLA1) exhibiting an IC50 of 210 nM for APT1 enzymatic inhibition By blocking the catalytic site of APT1 ML348 impairs the depalmitoylation of proteins thereby modulating the dynamic balance of protein palmitoylation within cells This compound is widely employed in studies investigating protein post-translational modifications and the associated cellular signaling pathways facilitating the elucidation of the functional roles and regulatory mechanisms of protein palmitoylation
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