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Medchemexpress LLC ML-792 | 1644342-14-2 | 99.8% | 551.41 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY10870250MG

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ML-792 is a potent and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays, with IC50 values of 3 nM and 11 nM, respectively. It demonstrates significantly less activity against NAE/NEDD8 and UAE/ubiquitin. This product is for research use only.

  • Potent and selective inhibitor of SAE/SUMO1 and SAE/SUMO2.
  • IC50 values of 3 nM for SAE/SUMO1 and 11 nM for SAE/SUMO2.
  • Significantly less activity against NAE/NEDD8 and UAE/ubiquitin.
  • Purity: 99.76%.
  • CAS number: 1644342-14-2.
  • Molecular weight: 551.41.
  • Appearance: solid, white to off-white.
  • Inhibits SAE and SUMO-pathway activities in HCT116 cells.
  • Inhibits cell proliferation and decreases cancer cell viability.
  • Demonstrates dose-dependent viability effect.
  • Revealed dose-dependent decrease in SAE and UBC9 thioester levels.
  • Soluble in DMSO: 100 mg/mL (181.35 mM).

Catalog No. 50-003-45397


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