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Apexbio Technology LLC MLN4924 HCl salt 1160295-21-5 1mg
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Catalog No. 5000093744
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MLN4924 HCl salt (CAS 1160295-21-5) is a small molecule inhibitor that selectively targets the NEDD8-activating enzyme (NAE) By blocking NAE-mediated neddylation MLN4924 disrupts the activation of cullin-RING E3 ubiquitin ligases resulting in the accumulation of specific protein substrates involved in cell cycle regulation DNA replication and apoptosis This compound is widely utilized in biomedical research to investigate protein homeostasis ubiquitin-proteasome system function and the therapeutic potential of NAE inhibition in cancer and other proliferative diseases

Catalog No. 50-000-93744 Supplier Apexbio Technology LLC Supplier No. A36291
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MLN4924 HCl salt (CAS 1160295-21-5) is a small molecule inhibitor that selectively targets the NEDD8-activating enzyme (NAE) By blocking NAE-mediated neddylation MLN4924 disrupts the activation of cullin-RING E3 ubiquitin ligases resulting in the accumulation of specific protein substrates involved in cell cycle regulation DNA replication and apoptosis This compound is widely utilized in biomedical research to investigate protein homeostasis ubiquitin-proteasome system function and the therapeutic potential of NAE inhibition in cancer and other proliferative diseases

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