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Apexbio Technology LLC MLN8237 (Alisertib) 1028486-01-2 10mM (in 1mL DMSO)
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Supplier:  Apexbio Technology LLC A41105.1

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MLN8237 (Alisertib CAS 1028486-01-2) is an orally administered small molecule inhibitor targeting Aurora A kinase (AAK) an enzyme frequently overexpressed in various cancers and linked to tumor proliferation and progression Developed from its predecessor MLN8054 to reduce benzodiazepine-like side effects MLN8237 potently inhibits Aurora A kinase through reversible ATP-competitive binding (Ki 0 43 nmol/L) Given its demonstrated anti-tumor activity in preclinical in vitro and in vivo studies MLN8237 is currently under investigation for treating advanced malignancies

Catalog No. 50-000-61536


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