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Medchemexpress LLC MM-401 TFA | 1442106-11-7 | 99.3% | 700.75 | 1 MG
SDP

Supplier:  Medchemexpress LLC HY19554A1MG

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MM-401 (TFA) is an MLL1 H3K4 methyltransferase inhibitor. It inhibits MLL1 activity with an IC50 of 0.32 μM by blocking the MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis, and differentiation and can be used for research into MLL leukemia.

  • Target specificity: Inhibits MLL1 H3K4 methyltransferase activity by blocking MLL1-WDR5 interaction.
  • Potency: Inhibits MLL1 activity with an IC50 of 0.32 μM and disrupts WDR5-MLL1 interaction with an IC50 value of 0.9 nM.
  • Cellular effects: Induces cell cycle arrest, apoptosis, and differentiation.
  • Research application: Useful for research of MLL leukemia.
  • Purity: 99.34%.

Catalog No. 50-004-01846


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