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Medchemexpress LLC MM-401 (TFA) | 1442106-11-7 | 99.3% | 700.75 | 5 MG
Supplier: Medchemexpress LLC HY19554A5MG
MM-401 (TFA) is an inhibitor of MLL1 H3K4 methyltransferase. It works by blocking the interaction between MLL1 and WDR5, thereby inhibiting MLL1 activity with an IC50 of 0.32 μM. This compound can induce cell cycle arrest, apoptosis, and differentiation. It is used in research for MLL leukemia.
- Inhibits MLL1 H3K4 methyltransferase
- Blocks MLL1-WDR5 interaction
- Potent inhibition of MLL1 activity
- Induces cell cycle arrest
- Promotes apoptosis
- Facilitates differentiation
- Useful for research of MLL leukemia
- Specifically inhibits MLL1-dependent H3K4 methylation in cells
- Inhibits growth of MLL leukemia cells
- Affects MLL-AF9 transcriptome
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