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Enzo Life Sciences Matrix Metalloproteinase-13 (MMP-13) fluorometric drug discovery kit (1x96wells)
SDP

Supplier:  Enzo Life Sciences BMLAK4130001

Encompass_Preferred

A QUANTIZYME Assay System. The MMP-13 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-13 (MMP-13, collagenase-3) using a quenched fluorogenic peptide: OMNIMMP fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties. The assays are performed in a convenient 96-well microplate format. The kit is useful to screen inhibitors of MMP-13, a potential therapeutic target. Included are active enzyme, assay buffer, a prototypic control inhibitor (NNGH3), and a detailed instruction booklet. Alternative name: Collagenase 3. Applications: Fluorescent detection, HTS Activity assay.

Catalog No. 50-201-0273


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