Enzo Life Sciences MMP-14 (catalytic domain) (human), (recombinant) (10 µg)

Supplier:  Enzo Life Sciences BMLSE2590010

Alternative name: Matrix metalloproteinase 14. Membrane type matrix metalloproteinase 1. MT-1 MMP. MW: 22.5 kDa. Formulation: Liquid. In 50mM TRIS, pH 7.5, containing 5mM calcium chloride, 300mM sodium chloride, 20µM zinc chloride, 0.5% Brij-35, and 30% glycerol. Source: Produced in E.coli. MMP-14, Membrane-Type Matrix Metalloproteinase 1, MT1-MMP catalytic domain from human cDNA. The enzyme consists of the catalytic domain of human MMP-14 (Tyr112-Arg298, NM_004995) with a C-terminal purification tag. This represents a naturally-occurring active form of MMP-14 which lacks the C-terminal hemopexin domain. MMPs lacking this domain cannot cleave native collagens; however, activity toward other targets such as gelatin. CASein, or peptide substrates is unaffected. Use/Stability: The enzyme is stable on ice for at least several hours. However, it is recommended that thawing and dilution of the enzyme be done within as short a time as possible before start of the assay.

Catalog No. NC1181308