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Creative Biomart Recombinant Human MMP14(Membrane-inserted), Catalytic Domain

Supplier:  Creative Biomart MMP14160H50UG

Encompass

Description :Matrix metalloproteinase-14 is an enzyme that in humans is encoded by the MMP14 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP"s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

Catalog No. NC1343841


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