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Cayman Chemical Mn III ProtoporphyrIn IX Chl
Supplier: Cayman Chemical 30808500 MG
A broad-spectrum synthetic fluoroquinolone antibiotic active against Gram-negative and Gram-positive bacteria including clinical isolates of E coli K pneumoniae methicillin-susceptible and -resistant S aureus and methicillin-susceptible and -resistant S epidermidis (MIC90s 0 05 0 1 0 39 12 5 0 39 and 6 25 g/ml respectively) inhibits E coli P aeruginosa and S aureus DNA gyrase (IC50s 0 88 1 9 and 10 2 g/ml respectively) and S aureus topoisomerase IV (IC50 24 2 g/ml) in cell-free assays active against systemic E coli K pneumoniae and methicillin-resistant S aureus infections in mice (ED50s 0 15 5 5 and 4 5 mg/kg respectively)
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