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Apexbio Technology LLC Mocetinostat (MGCD0103, MG0103) 726169-73-9 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC A40895.1
Mocetinostat (MGCD0103 MG0103 CAS 726169-73-9) is an isotype-selective inhibitor of human histone deacetylases (HDACs) It selectively targets class I HDAC enzymes (HDAC1 HDAC2 HDAC3) and class IV HDAC11 without affecting class II HDACs Mocetinostat inhibits these isoforms with IC50 values of 0 15 mol/L (HDAC1) 0 29 mol/L (HDAC2) 1 66 mol/L (HDAC3) and 0 59 mol/L (HDAC11) resulting in histone hyperacetylation cell cycle arrest and apoptosis in various cancer cell lines It serves as a research tool for studying epigenetic regulation and as a candidate compound for anticancer drug development
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