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Cayman Chemical MoclobemIde-d4 10mg
SDP

Supplier:  Cayman Chemical 3424710 MG

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A noncompetitive antagonist and inverse agonist of mGluR5 that binds to an allosteric site inhibits quisqualate-induced intracellular calcium mobilization in HEK293 cells expressing the human receptor (IC50 58 nM) inhibits basal activity of mGluR5 in a cell-based assay (IC50 84 nM) reduces stress-induced hyperthermia in mice at 10 and 30 mg/kg increases drinking time in the Vogel conflict test in rats at 30 mg/kg induces analgesia in the formalin test in mice at 30 mg/kg

Catalog No. 50-294-8232


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