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Medchemexpress LLC Mocravimod hydrochloride | 509088-69-1 | 99.99% | 480.45 | 25 MG
Supplier: Medchemexpress LLC 25MGHY13660
Mocravimod hydrochloride is an orally active sphingosine-1-phosphate receptor (S1PR) modulator that blocks the signal T cells need to egress from lymph nodes and other lymphoid organs. It preferentially binds to S1PR1 and can be used for the study of acute myelogenous leukemia, diabetes, and Myocardial Ischemia-Reperfusion Injury (MIRI).
- Blocks T cell egress from lymph nodes
- Preferentially binds to S1PR1
- Lowers reactive oxygen species (ROS) concentration
- Prevents mitochondrial permeability transition pore opening
- Boosts mitochondrial membrane potential (MMP)
- Increases phosphorylation of AKT, EKR, GSK-3β, JAK2, and STAT3
- Retains T cell effector function
- Suitable for studying acute myelogenous leukemia, diabetes, and Myocardial Ischemia-Reperfusion Injury (MIRI)
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