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Medchemexpress LLC Moexipril (hydrochloride) | 82586-52-5 | 1 ML
Supplier: Medchemexpress LLC HYB0378A10MM/1ML
Moexipril hydrochloride is an orally active inhibitor of angiotensin-converting enzyme (ACE) that becomes effective after being hydrolyzed to moexiprila (hydrochloride). It demonstrates antihypertensive and neuroprotective effects and exhibits high potency against both plasma ACE and purified ACE from rabbit lung.
- Functions as an orally active ACE inhibitor
- Becomes effective after hydrolysis to moexiprila
- Demonstrates antihypertensive and neuroprotective effects
- High potency against plasma ACE and purified ACE from rabbit lung
- Reduces damaged neurons in a dose-dependent manner
- Attenuates Fe2+/3+-induced neurotoxicity
- Exhibits dose-dependent antihypertensive effects in various hypertensive rat and dog models
- Significantly reduces infarct area and cortical infarct volume in mouse and rat models of ischemic brain injury
- Supplied as a 10 mM solution in DMSO
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