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Medchemexpress LLC Moexipril (hydrochloride) | 82586-52-5 | 98.4% | 25 MG
Supplier: Medchemexpress LLC 25MGHYB0378A
Moexipril hydrochloride is an orally active inhibitor of angiotensin-converting enzyme (ACE) that becomes effective after being hydrolyzed to moexiprilat (hydrochloride). This compound demonstrates significant antihypertensive and neuroprotective effects.
- Orally active inhibitor of angiotensin-converting enzyme (ACE).
- Becomes effective after hydrolysis to moexiprilat.
- Exhibits antihypertensive and neuroprotective effects.
- High potency against plasma ACE and purified ACE from rabbit lung.
- Significantly reduces damaged neurons in a dose-dependent manner.
- Attenuates Fe2+/3+-induced neurotoxicity.
- Does not cause significant changes in apoptotic neurons.
- Does not cross the blood-brain barrier.
- Shows dose-dependent antihypertensive effects in various animal models.
- Reduces infarct area on mouse brain surface.
- Attenuates cortical infarct volume in rat brain.
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