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Moexipril hydrochloride, Tocris Bioscience™

Catalog No. 269150
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Catalog No. Quantity
26-915-0 50 mg
26-911-0 10 mg
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Catalog No. 26-915-0 Supplier R&D Systems Supplier No. 2691/50
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Description

Angiotensin-converting enzyme (ACE) inhibitor

Angiotensin-converting enzyme (ACE) inhibitor that is hydrolyzed in the liver to the active metabolite moexiprilat (IC 50 values are 2.1 and 2700 nM for moexiprilat and moexipril respectively). Antihypertensive; decreases mean blood pressure in the spontaneous hypertensive rat (SHR). Also blocks degradation of bradykinin into inactive metabolites.

Chemical Identifiers

CAS 82586-52-5
Molecular Formula C27H35ClN2O7
Molecular Weight (g/mol) 535.03
MDL Number MFCD00940481
InChI Key JXRAXHBVZQZSIC-JKVLGAQCSA-N
Synonym moexipril hydrochloride, moexipril hcl, unii-q1umg3uh45, moexipril hydrochloride usan, q1umg3uh45, univasc tn, dsstox_cid_24267, dsstox_rid_80137, dsstox_gsid_44267
PubChem CID 54889
IUPAC Name hydrogen (3S)-2-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid chloride
SMILES [H+].[Cl-].CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N1CC2=CC(OC)=C(OC)C=C2C[C@H]1C(O)=O

Specifications

Quantity 50 mg
Formula Weight 535.03
Percent Purity >99%
Chemical Name or Material Moexipril hydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
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