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Enzo Life Sciences Momelotinib (1mg). CAS: 1056634-68-4

Supplier: Enzo Life Sciences ENZCHM1970001
Using ATP kinase assays, the IC50 values for CYT387 are a follows - JAK1 (11nM), JAK2, (18nM), JAK2 V617F (23nM) JAK3 (155nM), and TYK2 (17nM). In testing kinase arrays, CYT387 also had activity (defined as an IC50 < 100nM) detected against CDK2/cyclin A, MAPK8 (JNK1), PRKCN (PKD3), PRKD1 (PKCμ), ROCK2, and TBK1 kinase as well. Alternative name: CYT 387, N-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]-benzamide. Purity: ≥97% (HPLC). Solubility: Soluble in DMSO (>20mM). Long Term Storage: -20°C.
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