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Apexbio Technology LLC Mometasone furoate 83919-23-7 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC B19795.1
Mometasone furoate (83919-23-7) is a glucocorticoid receptor agonist targeting intracellular glucocorticoid receptors It is designed to modulate glucocorticoid signaling pathways thereby regulating gene expression linked to inflammatory and allergic responses Mometasone furoate exerts its biological activity primarily through binding to cytoplasmic glucocorticoid receptors forming an activated complex that translocates into the nucleus and modulates target gene transcription This mechanism suppresses inflammatory cytokine production and inhibits inflammatory mediator release Based on these pharmacological properties Mometasone furoate holds research potential in experimental models of skin inflammatory disorders such as eczema and psoriasis as well as respiratory inflammatory processes including asthma
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