Monensin sodium salt, 90% min., Thermo Scientific Chemicals

Catalog No.	Quantity
AAJ6166903	1 g

Catalog No. AAJ6166903 Supplier Thermo Scientific Chemicals Supplier No. J6166903

Description

Monensin sodium salt is used in potentiometric and spectroscopic studies of alkali metal ion complexes. Monensin (Na) is a polyether small molecule ionophore, capable of forming stable complexes to monovalent cations with specific affinity for Na+. Monensin presents a highly lipophilic scaffold around the bound ion, allowing movement of the complex through the lipid bilayer and consequent transport of the ion out of the cell. Excessive flux of ions out of the cell produces a cytotoxic effect and generates the antibiotic properties of Monensin.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Monensin sodium salt is used in potentiometric and spectroscopic studies of alkali metal ion complexes. Monensin (Na) is a polyether small molecule ionophore, capable of forming stable complexes to monovalent cations with specific affinity for Na+. Monensin presents a highly lipophilic scaffold around the bound ion, allowing movement of the complex through the lipid bilayer and consequent transport of the ion out of the cell. Excessive flux of ions out of the cell produces a cytotoxic effect and generates the antibiotic properties of Monensin.

Solubility
Soluble in methanol at 50mg/ml

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Specifications

Chemical Identifiers

• CAS: 22373-78-0
• Molecular Formula: C36H61NaO11
• Molecular Weight (g/mol): 692.863
• MDL Number: MFCD00077826
• InChI Key: XOIQMTLWECTKJL-JXDONITHSA-M
• Synonym: monensin, sodium salt, high purity, monensin sodium salt, monensin, monosodium salt, 4.5 dec-7-yl 3s,4r-3-methoxy-2-me thylpentanoic acid, sodium salt, 4-2-5-3r-5-3s,5r,6r-6-hydroxy-6-hydroxymethyl-3,5-dimethyl 2h-3,4,5, 6-tetrahydropyran-2-yl-3-methyloxolan-2-yl 5s-5-ethyloxolan-2-yl 5s,8s,2r ,9r-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro, 4-2-2-ethyl-5'-6-hydroxy-6-hydroxymethyl-3,5-dimethyltetrahydro-2h-pyran-2-yl-3'-methyloctahydro-2,2'-bifuran-5-yl-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro 4.5 decane-7-yl-3-methoxy-2-methylpentanoic acid sodium salt, potassium 4-2-5-ethyl-5-5-6-hydroxy-6-hydroxymethyl-3,5-dimethyloxan-2-yl-3-methyloxolan-2-yl oxolan-2-yl-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro 4.5 decan-7-yl-3-methoxy-2-methylpentanoate
• PubChem CID: 133612076
• IUPAC Name: sodium;(3S,4R)-4-[(2R,5S,7R,8S,9R)-2-[(2S,5R)-5-ethyl-5-[(2S,3R,5S)-5-[(2R,3R,5S,6S)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]oxolan-2-yl]-7-hydroxy-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]-3-methoxy-2-methylpentanoate
• SMILES: CCC1(CCC(O1)C2(CCC3(O2)CC(C(C(O3)C(C)C(C(C)C(=O)[O-])OC)C)O)C)C4C(CC(O4)C5C(CC(C(O5)(CO)O)C)C)C.[Na+]

• Melting Point: 267°C to 269°C
• Color: White
• Quantity: 1 g
• UN Number: UN3462
• Beilstein: 4122200
• Merck Index: 14,6246
• Solubility Information: Soluble in methanol at 50mg/ml
• Formula Weight: 692.86
• Percent Purity: 90 to 95.5%
• Physical Form: Powder
• Chemical Name or Material: Monensin sodium salt

Safety and Handling

Hazard Category	H300
Hazard Statement	GHS H Statement H300 Fatal if swallowed.
Precautionary Statement	P264b-P270-P301+P310-P330-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXINS, EXTRACTED FROM LIVING SOURCES, SOLID, N.O.S.
EINECSNumber	244-941-7
RTECSNumber	JH2830000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only