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Sigma Aldrich Fine Chemicals Biosciences Monoamine Oxidase Activity
Supplier: Sigma Aldrich Fine Chemicals Biosciences MAK1361KT
Monoamine oxidases (MAO EC 1.4.3.4) are a family of mitochondrial enzymes that catalyze the oxidative deamination of monoamines. In mammals MAO consists of two isoenzymes MAO-A and MAO-B. MAO dysfunction is thought to be responsible for a number of neurological disorders. Unusually high or low levels of MAO in the body have been associated with depression schizophrenia substance abuse attention deficit disorder migraines and irregular sexual maturation. MAO inhibitors are one of the major classes of drug prescribed for the treatment of depression.
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