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Medchemexpress LLC Monobenzone | 103-16-2 | MFCD10687031 | 99.9% | 200.24 | 100 G
SDP

Catalog No. 5000400480
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Monobenzone is a potent skin depigmenting agent with potential for vitiligo research. It also acts as an inhibitor of RNR enzyme activity, targeting the RRM2 protein. This demonstrates significant anti-leukemia efficacy both in vitro and in vivo, by inhibiting acute myeloid leukemia (AML) cell proliferation and DNA synthesis, and inducing cell cycle arrest and apoptosis.

  • Inhibits AML cell proliferation and DNA synthesis.
  • Induces cell cycle arrest and apoptosis in various AML cell lines.
  • Blocks DNA damage repair.
  • Can overcome drug resistance in certain cell lines.
  • Synergistically inhibits cell growth with Bcl-2 inhibitor.
  • Induces skin depigmentation in mice.
  • Effectively inhibits AML cell xenograft growth in nude mice with low toxicity.

Catalog No. 50-004-00480 Supplier Medchemexpress LLC Supplier No. HY30272100G
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Monobenzone is a potent skin depigmenting agent with potential for vitiligo research. It also acts as an inhibitor of RNR enzyme activity, targeting the RRM2 protein. This demonstrates significant anti-leukemia efficacy both in vitro and in vivo, by inhibiting acute myeloid leukemia (AML) cell proliferation and DNA synthesis, and inducing cell cycle arrest and apoptosis.

  • Inhibits AML cell proliferation and DNA synthesis.
  • Induces cell cycle arrest and apoptosis in various AML cell lines.
  • Blocks DNA damage repair.
  • Can overcome drug resistance in certain cell lines.
  • Synergistically inhibits cell growth with Bcl-2 inhibitor.
  • Induces skin depigmentation in mice.
  • Effectively inhibits AML cell xenograft growth in nude mice with low toxicity.

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