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Sigma Aldrich Fine Chemicals Biosciences Monoclonal Anti Collagen T
Supplier: Sigma Aldrich Fine Chemicals Biosciences C1926100UL
The composition of the extracellular matrix of all vertebrates is dominated by a class of molecules known as collagens each with a unique feature suited to its function and location. Type IV collagen is a major constituent of basement membranes. This molecule is a continuous triple helix about 400 nm in length composed of at least two different chain subunits termed1 (IV) and2 (IV) which may be composed of the same or different molecules. Upon proteolysis fragments of 125 kDa 95 kDa and 60 kDa are released from a parent1 (IV) chain whereas fragments of 115 kDa 80 kDa and 45 kDa apparently originate from a distinct2 (IV) chain.
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