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Cayman Chemical MosaprIdecItrate 100mg

Supplier: Cayman Chemical 30048100 MG

A Nur77 receptor agonist selectively activates Nur77 over PPARY in reporter assays at 20 M inhibits growth of and induces apoptosis in L3 6pL pancreatic cancer cells at 10 15 and 20 M stabilizes nuclear localization of Nur77 and Nurr1 and reduces secretion of pro-inflammatory cytokines in primary mouse astrocytes oral administration prevents loss of dopaminergic neurons in the substantia nigra pars compacta and striatal dopamine terminals in a mouse model of MPTP-induced Parkinsons disease at 50 mg/kg
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