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Medchemexpress LLC Motolimod | 926927-61-9 | 98.1% | 458.60 | 250 MG
Supplier: Medchemexpress LLC 250MGHY13773
Motolimod (VTX-2337; VTX-378) is a selective Toll-like receptor 8 (TLR8) agonist with an EC50 of approximately 100 nM. It selectively activates TLR8 among other tested TLRs, stimulating the production of TNFα and IL-12 in PBMCs. This compound is intended for research use only and is not sold to patients.
- Selective TLR8 agonist with high specificity
- Stimulates production of TNFα and IL-12 in PBMCs
- Induces MIP-1β production
- Increases plasma levels of IL-1β and IL-18 in vivo
- Supports NK cell activation through IFNγ
- Evaluated in clinical trials for oncology research
- Available as a solid, light yellow to brown powder
- Soluble in DMSO for in vitro applications
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