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Mouse anti-Human IgD, Secondary Antibody, BD

Catalog No. BDB562540 Shop All BD Biosciences Products
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BDB562540 50 Tests
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Description

The IA6-2 monoclonal antibody specifically binds to the heavy chain of human Immunoglobulin D (IgD). IgD is a member of the immunoglobulin superfamily that exists in type 1-membrane (mIgD) and soluble glycoprotein forms. mIgD is expressed on mature naive B cells (along with membrane IgM) and serves as a B-cell receptor for antigen (BCR). In response to antigen binding, the mIgD BCR, in association with other signaling molecules including CD79a and CD79b, can transduce activating or tolerizing signals intracellularly into B lymphocytes. This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™. PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics. Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488nm), green (532nm) and yellow-green (561nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg 610/20nm filter).

Host Species: Mouse
Clone: IA6-2
Isotype: IgG2a, κ
Species Reactivity: Human

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen Human IgD
Classification Monoclonal
Clone IA6-2
Conjugate PE-CF594
Host Species Mouse
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Secondary
Target Species Human
Isotype IgG2a κ
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