Gibco™ Mouse APRIL Recombinant Protein, PeproTech®

Catalog No.	Quantity
31513100UG	100 μg
315-13-1MG	1 mg
315-13-20UG	20 μg
31513250UG	250 μg
31513500UG	500 μg
315-13-5UG	5 μg

Catalog No. 31513100UG Supplier Gibco™ Supplier No. 31513100UG

Description

Recombinant Protein

Recombinant Murine APRIL is a soluble 21.9 kDa protein, consisting of 192 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.

Specifications

• Accession Number: Q9D777
• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 69583
• Molecular Weight (g/mol): 21.9 kDa
• Name: Mouse APRIL
• Quantity: 100 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: 2310026N09Rik; A proliferation-inducing ligand; APRIL; CD256; TALL2; TALL-2; TNF- and APOL-related leukocyte expressed ligand 2; TNF-related death ligand 1; Tnfsf13; TNLG7B; Trdl1; TRDL-1; tumor necrosis factor (ligand) superfamily, member 13; tumor necrosis factor ligand 7 B; tumor necrosis factor ligand superfamily member 13; tumor necrosis factor superfamily member 13; tumor necrosis factor-like protein ZTNF2; tumor necrosis factor-related death ligand-1; UNQ383/PRO715; ZTNF2
• Common Name: APRIL
• Gene Symbol: TNFSF13
• Biological Activity: Measured by its ability to induce cell proliferation of activated T cells.
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: MRREVSRLQR SGGPSQKQGE RPWQSLWEQS PDVLEAWKDG AKSRRRRAVL TQKHKKKHSV LHLVPVNITS KDSDVTEVMW QPVLRRGRGL EAQGDIVRVW DTGIYLLYSQ VLFHDVTFTM GQVVSREGQG RRETLFRCIR SMPSDPDRAY NSCYSAGVFH LHQGDIITVK IPRANAKLSL SPHGTFLGFV KL
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.