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  4. Gibco™ Mouse CD40 Ligand (TNFSF5) (soluble) Recombinant Protein, PeproTech® 

Gibco™ Mouse CD40 Ligand (TNFSF5) (soluble) Recombinant Protein, PeproTech®

Catalog No. p-7246195
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1 mg
100 μg
25 μg
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500 μg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Recombinant Protein

Recombinant Murine CD40L is a soluble 16.4 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CD40L. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen expressed on the surface of T cells. The CD40 Ligand stimulates B cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 Ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P27548
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 21947
Molecular Weight (g/mol) 16.4 kDa
Name Mouse CD40 Ligand (TNFSF5) (soluble)
Quantity 100 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40L; CD40-L; Cd40lg; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; TNFSF5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5
Common Name CD154 (CD40 Ligand)
Gene Symbol CD40LG
Biological Activity Determined by its ability to induce TNF-alpha and MIP-1 alpha production by murine splenocytes. The expected ED50 for this effect is < 0.1 ug/ml
Conjugate Unconjugated
Recombinant Recombinant
Sequence MQRGDEDPQI AAHVVSEANS NAASVLQWAK KGYYTMKSNL VMLENGKQLT VKREGLYYVY TQVTFCSNRE PSSQRPFIVG LWLKPSSGSE RILLKAANTH SSSQLCEQQS VHLGGVFELQ AGASVFVNVT EASQVIHRVG FSSFGLLKL
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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