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Gibco™ Mouse Flt-3 Ligand (FLT3L), AOF Recombinant Protein

Catalog No. PIRP87737 Shop All Thermo Scientific Products
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500 μg
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PIRP87737 500 μg
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Catalog No. PIRP87737 Supplier Gibco™ Supplier No. RP87737
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Description

Recombinant Protein

Animal Origin Free Reconstitute with 0.1 mg/mL sterile water.

FLT3LG (Fms Related Tyrosine Kinase 3 Ligand) is a Protein Coding gene. Diseases associated with FLT3LG include Aplastic Anemia and Brain Cancer. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Ras signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and cytokine activity. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P49772
Concentration 0.1 mg/mL
For Use With (Application) Bioactivity
Formulation 10mM sodium phosphate with no preservative; pH 7.5
Gene ID (Entrez) 14256
Molecular Weight (g/mol) 18.6 kDa
Name Mouse Flt-3 Ligand (FLT3L), AOF
pH Range 7.5
Purification Method Purified
Quantity 500 μg
Source E. coli
Storage Requirements -20°C
Regulatory Status RUO
Endotoxin Concentration ≤0.1 EU/μg
Gene Alias FL; Flt 3 ligand; Flt3; Flt3 L; Flt3 ligand; Flt3l; Flt3lg; fms related receptor tyrosine kinase 3 ligand; fms related tyrosine kinase 3 ligand; FMS-like tyrosine kinase 3 ligand; fms-related tyrosine kinase 3; fms-related tyrosine kinase 3 ligand; H-FLT-3-L; Ly72L; M-FLT-3-L; NEWGENE_2322792; SL cytokine
Common Name FLT3LG
Gene Symbol Flt3l
Biological Activity ED50 =10 ng/mL; determined by the dose-dependent proliferation of OCI-AML5 cells.
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Sequence MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ
Content And Storage -20°C
Activity ED50 ≤10 ng/mL; determined by the dose-dependent proliferation of OCI-AML5 cells.
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥95% by SDS-PAGE
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