This biotinylated mouse Her2 (ErbB2) protein is expressed from HEK293 cells, spanning Thr 23 to Thr 653 (Accession # P70424). HER2 is a cell membrane-bound receptor tyrosine kinase involved in signal transduction pathways that regulate cell growth and differentiation. The protein is produced with a human IgG1 Fc tag at the C-terminus, followed by an Avi tag, and is enzymatically labeled with biotin using Avitag™ technology.
- Calculated molecular weight of 97.8 kDa, migrating at 110-130 kDa under reducing conditions due to glycosylation
- Purity >90% by SDS-PAGE and >95% by SEC-MALS
- Lyophilized from 0.22 μm filtered PBS, pH 7.4 with trehalose
- Stable for 12 months at -20°C or lower in lyophilized state
- Please consult the Certificate of Analysis for specific reconstitution instructions