Invitrogen™ Mouse IL-17BR ELISA Kit

Description

ELISA

Mouse IL-17BR quantitates mouse IL-17BR in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse IL-17BR.

Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.

Specifications

• Accession Number: CRL4; cytokine receptor CRL4; cytokine receptor-like 4; ecotropic viral integration site 27; Evi27; IL-17 receptor B; IL-17 receptor homolog 1; IL-17 B; IL-17 B receptor; IL17BR; IL-17 ER; IL17RB; IL-17 RB; IL17RH1; IL-17 Rh1; IL-20; interleukin 17 receptor B; interleukin 17 receptor homolog 1; interleukin 17 B receptor; Interleukin-17 receptor B; interleukin-17 B receptor; MGC138900; MGC138901; MGC5245; UNQ2501/PRO19612; ZCYTO7
• Assay Range: 0.2 to 50 ng/mL
• Assay Sensitivity: 0.2 ng/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 50905
• Gene Symbol: IL17RB
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Storage Requirements: 2°C to 8°C
• Target: IL17RB
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov