Gibco™ Mouse IL-18 Recombinant Protein

Catalog No.	Quantity
PMC0184	25 μg

Catalog No. PMC0184 Supplier Gibco™ Supplier No. PMC0184

Description

Recombinant Protein

Reconstitution: We recommend that the vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the contents of the vial with 250 μL ice cold, sterile, distilled water on ice. Storage: Store this lyophilized preparation at -20°C, preferably desiccated. Upon reconstitution, the protein may be stored at 2°C to 8°C for up to one week. For long term storage of the reconstituted protein, apportion into working aliquots and store at -80°C. Avoid repeated freeze/thaw cycles.

The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein can specifically interact with this cytokine, and thus negatively regulate its biological activity.

Specifications

• Accession Number: P70380
• For Use With (Application): Bioactivity
• Formulation: PBS with 0.1% BSA, 1% sucrose and no preservative
• Gene ID (Entrez): 16173
• Molecular Weight (g/mol): 18 kDa
• Name: Mouse IL-18
• Purification Method: Purified
• Quantity: 25 μg
• Storage Requirements: -20°C
• Regulatory Status: RUO
• Endotoxin Concentration: <0.1 ng/μg
• Gene Alias: cytokine; iboctadekin; IFN-gamma-inducing factor; IGIF; il 18; IL-1 gamma; IL18; IL-18; IL1F4; IL-1g; ILN; interferon gamma inducing factor; interferon gamma-inducing factor; interferon-gamma-inducing factor; Interleukin; interleukin 18; interleukin 18 (interferon-gamma-inducing factor); interleukin-1 gamma; Interleukin18; Interleukin-18; interleukin-18 proprotein; interleukin-18-like protein; MGC12320
• Common Name: IL-18
• Gene Symbol: IL18
• Biological Activity: Determined by the dose-dependent induction of IFN-gamma production in mouse IL-18 receptor transfected KG-1 cells.
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Mouse
• Recombinant: Recombinant
• Sequence: Mouse IL-18, amino acids 36-192 of the mature sequence
• Content And Storage: -20°C
• Activity: Determined by the dose-dependent induction of IFN-gamma production in mouse IL-18 receptor transfected KG-1 cells.
• Endotoxin Level: <0.1 ng/μg
• Shipping Condition: Approved for shipment on Wet or Dry Ice
• Expression System: E. coli
• Protein Family: Cytokines & Receptors
• Protein Form: Recombinant, Ligand
• Form: Lyophilized
• Protein Subtype: Interleukins
• Research Category: Immunology, Neurobiology, Inflammation, Angiogenesis, Signal Transduction
• Product Line: Gibco
• Purity or Quality Grade: >90% by SDS-PAGE