Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ eBioscience™ Mouse MCPT-1 (mMCP-1) ELISA Ready-SET-Go!™ Kit Non-distribution product as customer accommodation.

Optimized for the accurate and precise measurement of mouse MCPT-1 in serum, and tissue culture supernatant samples. MCPT-1 (Mast Cell Protease-1) is a β-chymase, a type of serine protease stored and secreted in a tissue-specific manner by mucosal mast cells.

Manufacturer:  Invitrogen™ 88750386

 View more versions of this product

Catalog No. 50-174-17

Add to cart

Includes: Capture Antibody: Pre-titrated, purified antibody
Detection Antibody. Pre-titrated, biotin-conjugated antibody
Standard. Recombinant protein for generating standard curve and calibrating samples
Coating Buffer. 10X PBS ELISA Coating Buffer
Assay Diluent. 5X Concentrated
Detection Enzyme. Pre-titrated Avidin-HRP
Substrate Solution. Tetramethylbenzidine (TMB) Solution
Certificate of Analysis. Lot-specific instructions for the dilution of antibodies and standards



MCPT-1 is the only chymase expressed by intestinal mucosal mast cells, which are found in the intestinal epithelium. Although it is expressed constitutively and is detectable in the sera of normal mice, parasites in the gut cause systemic levels to increase dramatically within two days and peak at two weeks following infection. It plays an important role in host defense against intestinal parasites, as mice deficient in MCPT-1 display delayed response upon infection. Elevated MCPT-1 levels are also observed during intestinal allergic hypersensitivity reactions. The mechanism of its action is not fully understood, although it is believed to increase intestinal permeability similarly to rMCPT-II, possibly by cleaving the proteins at tight junctions between cells.


Colorimetric Microplate Reader
Serum, Supernatants
1 hr 45 min
Mouse Mast Cell Protease-1
120-15,000 pg/mL
96-well plates
96-Well Plates: Corning Costar flat-bottom plated (included with catalog numbers ending in -22 and -86)
10 x 96 tests
120 pg/mL
Serum (100μL), Supernatants (100μL)
24 hr 30 min
Provide Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

For Research Use Only