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ACROBiosystems Monoclonal Anti-MMAE Antibody, Mouse IgG1 (MME-M5252) is expressed from human 293 cells.
Supplier: ACROBiosystems MMEM5252100UG
Monomethyl auristatin E (MMAE) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types. Anti-MMAE antibody is a Mouse monoclonal antibody. This antibody has been shown to work in applications such as: PK, PD, Immunoassay and ELISA.
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